Top articles
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Comprehensive analysis of correlation coefficients estimated from pooling heterogeneous microarray data
The synthesis of information across microarray studies has been performed by combining statistical results of individual studies (as in a mosaic), or by combining data from multiple studies into a large pool to be analyzed as a single data set (as in...
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Michael Kruse: The Disease With No Name
Medicine can be tricky. Patients never present with the perfect cluster of disease-defining symptoms and when they do, it is so rare that you begin to think that they just read a textbook or Googled “heart attack" to fool you. As a patient, waiting for...
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F.D.A. Rule Could Open Generic Drug Makers to Suits
The Food and Drug Administration on Wednesday signaled its intention to permit generic drug makers to make changes to their safety labels, a move that could open the door to lawsuits against generic drug companies for the first time since a Supreme Court...
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Fewer meals may not mean fewer pounds for all, doctor warns of diabetic meal study
(CBS News) A new study on diabetics finds that eating two large meals a day leads to more weight loss than having six small meals. But that doesn’t mean you should change the way you diet, warns one expert. “It’s really important for people not to get...
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Well: Keeping Cancer a Secret
Andreas Rentsch/Getty Images My patient came to see me every six months or so with his wife of 40 years, making the five-hour drive from West Virginia, where he managed a few businesses. He had myelodysplastic syndrome, a type of bone marrow cancer that...
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Scientists uncover easy strategies to prevent harmful side-effects of antibiotics responses
A team of scientists at the Wyss Institute for Biologically Inspired Engineering at Harvard University has discovered why long-term treatment with many common antibiotics can cause harmful side effects-and they have uncovered two easy strategies that...
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Scientists uncover easy strategies to prevent harmful side-effects of antibiotics responses
A team of scientists at the Wyss Institute for Biologically Inspired Engineering at Harvard University has discovered why long-term treatment with many common antibiotics can cause harmful side effects-and they have uncovered two easy strategies that...
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Compartmentalized, functional role of angiogenin during spotted fever group rickettsia-induced endothelial barrier dysfunction: evidence of possible mediation by host tRNA-derived small noncoding RNAs
Microvascular endothelial barrier dysfunction is the central enigma in spotted fever group (SFG) rickettsioses. Angiogenin (ANG) is one of the earliest identified angiogenic factors, of which some are relevant to the phosphorylation of VE-cadherins that...
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South Africans resigned over 'critical' Mandela
JOHANNESBURG (Reuters) – South Africans appeared resigned on Monday to the inevitability of one day saying goodbye to former president Nelson Mandela after the 94-year-old anti-apartheid leader’s condition in hospital deteriorated to critical. Madiba,...
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Latest bird flu strain 'kills more than a third' of patients, Chinese researchers say
LONDON – More than a third of patients infected with a new strain of bird flu died after being admitted to the hospital earlier this year, Chinese researchers report in a new study. Since the new H7N9 bird flu first broke out in China in late March, the...
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Cambridge's Choir of King's College to give two concerts in August
Hong Kong (HKSAR) – The world-renowned Choir of King’s College from Cambridge in the UK will visit Hong Kong again in August for two concerts. The concerts will take place at 8pm on August 14 (Wednesday) at the Auditorium of Sha Tin Town Hall and at 8pm...
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Male desire for young women doesn't drive menopause
Research claiming that men are to blame for menopause has gone viral in the popular media in the past week. But does the theoretical model’s fundamental assumption – that men prefer young women – stack up? It may surprise some to discover that, in many...
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Finding Murray's magic
23-Jun-2013 [ | E-mail | ] Contact: PressofficePressoffice@esrc.ac.ukEconomic Social Research Council Research suggests that it is Andy Murray’s ability to manage his goals, as well as his skill, determination and motivation that makes him such a successful...
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NHS productivity in England increases by 3.2%, new study reveals
A new study by researchers at the Centre for Health Economics, University of York, reveals the productivity of the NHS in England increased by 3.2 per cent in the first year of the Coalition administration. Researchers at CHE used the most detailed and...
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NHS productivity in England increases by 3.2%, new study reveals
A new study by researchers at the Centre for Health Economics, University of York, reveals the productivity of the NHS in England increased by 3.2 per cent in the first year of the Coalition administration. Researchers at CHE used the most detailed and...
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The utility of single-balloon enteroscopy for the diagnosis and management of small bowel disorders according to their clinical manifestations: a retrospective review
The advent of double-balloon enteroscopy has enabled more accurate diagnosis and treatment of small bowel disorders. Single-balloon enteroscopy permits visualization of the entire small intestine less often than does double-balloon enteroscopy. However,...
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Spatial disaggregation of tick occurrence and ecology at a local scale as a preliminary step for spatial surveillance of tick-borne diseases: general framework and health implications in Belgium
The incidence of tick-borne diseases is increasing in Europe. Sub national information on tick distribution, ecology and vector status is often lacking. However, precise location of infection risk can lead to better targeted prevention measures, surveillance...
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Could a brief assessment of negative emotions and self-esteem identify adolescents at current and future risk of self-harm in the community? A prospective cohort analysis
Self-harm is common in adolescents, but it is often unreported and undetected. Available screening tools typically ask directly about self-harm and suicidal ideation. Although in an ideal world, direct enquiry and open discussion around self-harm would...
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Global end-diastolic volume increases to maintain fluid responsiveness in sepsis-induced systolic dysfunction
Sepsis-induced cardiac dysfunction may limit fluid responsiveness and the mechanism thereof remains unclear. Since cardiac function may affect the relative value of cardiac filling pressures, such as the recommended central venous pressure (CVP), versus...
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Home range plus: a space-time characterization of movement over real landscapes
Advances in GPS technology have created both opportunities in ecology as well as a need for analytical tools that can deal with the growing volume of data and ancillary variables associated with each location. Results: We present T-LoCoH, a home range...
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The environmental-data automated track annotation (Env-DATA) system: linking animal tracks with environmental data
The movement of animals is strongly influenced by external factors in their surrounding environment such as weather, habitat types, and human land use. With advances in positioning and sensor technologies, it is now possible to capture animal locations...
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LCQ3: Energy conservation
Hong Kong (HKSAR) - Following is a question by the Hon Elizabeth Quat and an oral reply by the Secretary for the Environment, Mr Wong Kam-sing, in the Legislative Council today (July 3):Question:It is learnt that the Secretary for the Environment has...
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Ofgem cracks down as cannabis farms steal electricity
LONDON (Reuters) - Cannabis farms are sucking millions of pounds worth of power off the Britain’s energy grid, the industry regulator said on Wednesday, as it announced a clamp down on electricity theft that will force power companies to act or face fines....
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LCQ8: Development of Hong Kong as an international asset management centre
Hong Kong (HKSAR) - Following is a question by the Hon Christopher Cheung and a written reply by the Secretary for Financial Services and the Treasury, Professor K C Chan, in the Legislative Council today (July 3):Question:The Financial Secretary mentioned...
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Test accurately and swiftly detect most leading causes of bacterial blood stream infection
2-Jul-2013 [ | E-mail | Share ] Contact: Fiona Godwinfgodwin@plos.org 01-223-442-834Public Library of Science A new automated diagnostic test can quickly and accurately identify most leading causes of Gram-positive bacterial blood stream infections and...